Fig. 4. Proposed model of signal transduction and regulatory controls for cercosporin biosynthesis and self-protection in Cercospora nicotianae. Light activates cercosporin biosynthesis through a network involved Ca²⁺/Calmodulin and MAP kinase pathways. The zinc cluster transcription factor, CRG1 regulates cluster genes including the specific pathway regulator CTB8. CTB8 induces the pathway.

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