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Inhibition of F-2 (Zearalenone) Biosynthesis and Perithecium Production in Fusarium roseum ‘Graminearum’. J. C. Wolf, Research Assistant, Department of Plant Pathology, University of Minnesota, St. Paul 55101; J. R. Lieberman(2), and C. J. Mirocha(3). (2)(3)Former Research Assistant, and Associate Professor, respectively, Department of Plant Pathology, University of Minnesota, St. Paul 55101. Phytopathology 62:937-939. DOI: 10.1094/Phyto-62-937.

Tracer incorporation studies and quantitative analysis showed that dichlorvos is a potent inhibitor of Zearalenone (F-2) biosynthesis by Fusarium roseum ‘Graminearum’. Dichlorvos also strongly inhibits production of perithecia by the fungus, and its inhibitory action can be reversed by F-2. This evidence suggests that F-2 may be a true fungal hormone which governs development of the sexual stage.