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The Plant Health Instructor

Volume: 03
Year: 2003
Article Type: Lesson Plans
​​​Antigen-Antibody Testing: A Visual Simulation or Virtual Reality

​Daniel Schadler

​Oglethorpe University

Date Accepted: 01 Jan 2003
Date Published: 01 Jan 2003
DOI: 

​10.1094/PHI-K-2003-0224-01

Keywords: antigen, antibody, VR




When a virus encounters an antibody that reacts with antigenic proteins in the viral particle, the virus and antibody clump together. When carried out under appropriate conditions, this clumping reaction will produce a visible product. Using real viruses and real antibodies to demonstrate this phenomenon is prohibitively expensive for most K-12 teachers. Less costly inorganic salts can be used to simulate the reaction. This demonstration is appropriate for life science courses that introduce the concepts of viruses, antigens and antibodies; it is also appropriate as a general demonstration of diffusion.

​Dr. Les Lane of the Department of Plant Pathology at the University of Nebraska, Lincoln, provided my initial exposure to this exercise.

Thomas Namey assisted in the preparation of Figures 6 and 7. ​​